Multimodal precision diagnostics in clinical xenotransplantation
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal precision diagnostic framework is proposed to detect these injuries earlier, guide personalized immunosuppression and inform future gene editing strategies.
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal precision diagnostic framework is proposed to detect these injuries earlier, guide personalized immunosuppression and inform future gene editing strategies.
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