RNA catalysis emerges from dynamic structural ensembles
Nature, Published online: 07 October 2026; doi:10.1038/s41586-026-11140-zRNase P RNA forms shifting active and inactive conformers whose catalytic activity depends on Mg2+-driven tertiary-interaction dynamics, which are modulated by binding of accessory proteins.
Nature, Published online: 07 October 2026; doi:10.1038/s41586-026-11140-zRNase P RNA forms shifting active and inactive conformers whose catalytic activity depends on Mg2+-driven tertiary-interaction dynamics, which are modulated by binding of accessory proteins.
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