Stimulation modulates gene-linked cell assemblies in the human brain

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10879-9Stimulation of human cortex reorganizes neural assemblies and induces cell-type-specific gene regulatory programs, establishing an ex vivo framework that links stimulation parameters to circuit and transcriptional responses for designing targeted neuromodulatory therapies.

SINSIN
Aug 5, 2026 - 22:00
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Stimulation modulates gene-linked cell assemblies in the human brain

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10879-9Stimulation of human cortex reorganizes neural assemblies and induces cell-type-specific gene regulatory programs, establishing an ex vivo framework that links stimulation parameters to circuit and transcriptional responses for designing targeted neuromodulatory therapies.

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