Tandem repeat variation shapes immune cell type-specific gene expression

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-10438-2Whole-genome sequencing and cell-level gene expression measurements show that length variation in tandem repeats in the human genome contributes to cell type-specific differences in gene regulation and expression, as well as the architecture of complex traits.

SINSIN
Oct 29, 2026 - 15:00
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Tandem repeat variation shapes immune cell type-specific gene expression

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-10438-2Whole-genome sequencing and cell-level gene expression measurements show that length variation in tandem repeats in the human genome contributes to cell type-specific differences in gene regulation and expression, as well as the architecture of complex traits.

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