A radical approach to making C-glycoside molecules
Nature, Published online: 22 July 2026; doi:10.1038/d41586-026-02237-6A platform for synthesizing highly desirable C-glycoside molecules from sugar has been developed that uses glycosyl sulfonyl hydrazides as readily accessible free-radical precursors. The strategy enables targeted formation of carbon–carbon bonds across carbohydrate scaffolds and with specificity for the desired 3D arrangement of atoms.
Nature, Published online: 22 July 2026; doi:10.1038/d41586-026-02237-6A platform for synthesizing highly desirable C-glycoside molecules from sugar has been developed that uses glycosyl sulfonyl hydrazides as readily accessible free-radical precursors. The strategy enables targeted formation of carbon–carbon bonds across carbohydrate scaffolds and with specificity for the desired 3D arrangement of atoms.
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