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De novo design of cysteine proteases

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11143-wDe novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.

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Oct 14, 2026 - 23:00
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De novo design of cysteine proteases

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11143-wDe novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.

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