Life

Synthesis of pyrroles from isoxazoles by an O-to-C skeletal edit

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.

SINSIN
Aug 19, 2026 - 22:00
 0  3
Synthesis of pyrroles from isoxazoles by an O-to-C skeletal edit

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.

Read More

Tags:

Previous Article

Multiyear tropical warm pool warming drives slowdown in Antarctic mass loss

Next Article

Discovery of a star sensitive to the spin of Sagittarius A*

What's Your Reaction?

like

dislike

love

funny

angry

sad

wow

SIN
SIN ScienceX Information Network (SIN) | ScienceX Innovations

Related Posts

How and when to use artificial intelligence in your science job application

How and when to use artificial intelligence in your sci...

SIN Aug 10, 2026  0  15

Meat allergy is on the rise — what scientists want to know

Meat allergy is on the rise — what scientists want to know

SIN Jul 31, 2026  0  19

This AI ‘Raygun’ can shrink and supersize proteins — opening the door to easy editing

This AI ‘Raygun’ can shrink and supersize proteins — op...

SIN Jul 29, 2026  0  27