Transcriptomic convergence and the female protective effect in autism

Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11236-6Gene network analysis shows how mutations in diverse genes associated with autism spectrum disorder can converge to exert shared effects, with X-linked transcription factor ZFX emerging as a key protective factor in the female brain.

SINSIN
Nov 5, 2026 - 03:00
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Transcriptomic convergence and the female protective effect in autism

Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11236-6Gene network analysis shows how mutations in diverse genes associated with autism spectrum disorder can converge to exert shared effects, with X-linked transcription factor ZFX emerging as a key protective factor in the female brain.

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