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An amygdala to anterior hypothalamic circuit gates stress sensitivity

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11075-5The anterior hypothalamic nucleus regulates negative valence in the brain, highlighting a new pathway that controls sensitivity to stressful events and signposting approaches to identify new circuit interactions relevant to mental health.

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Sep 30, 2026 - 23:00
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An amygdala to anterior hypothalamic circuit gates stress sensitivity

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11075-5The anterior hypothalamic nucleus regulates negative valence in the brain, highlighting a new pathway that controls sensitivity to stressful events and signposting approaches to identify new circuit interactions relevant to mental health.

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